Instruction: pick the one best answer. This is also useful on the USMLE step 1.
1. Which cell is a also called a septal cell?
a. Clara cell
b. Type I pneumocyte
c. Type II pneumocyte
d. Dust cell
e. Brush cell
Answer: c
The Clara cell is found in the terminal bronchioles. The type I pneumocyte is a squamous epithelial cell. It covers most of the surface of the alveoli. The type II pneumocyte is also called a septal cell. The type II pneumocyte secretes surfactant. The dust cell is also called the alveolar phagocyte. Brush cells are occasionally, but rarely, seen in the alveolar epithelium.
2.Which cell is a respiratory macrophage?
a. Kupffer cells
b. Histiocyte
c. Dust cell
d. Langerhans cell
e. Microglia
Answer: c
Macrophages are mononuclear phagocytes. Many tissues have resident (fixed) macrophages. Fixed macrophages are given a unique name, depending on the tissue that they are located in. Kupffer cells are the hepatic macrophages. Histiocytes are macrophages seen in connective tissue. Dust cells are alveolar macrophages found in the respiratory tract. Langerhans cells are macrophages seen in the skin. Microglia are the central nervous system macrophages.
3. Which cell is a type of neuron?
a. Basal cells
b. Brush cells
c. Olfactory cells
d. Sustentacular cells
e. All of the above
Answer: c
Olfactory mucosa lines the roof and portions of the walls of the nasal cavity. It contains several cell types: basal cells, brush cells, olfactory cells and sustentacular cells.
Basal cells are located in the basal lamina. Brush cells are involved with general sensation of the olfactory mucosa. Olfactory cells are bipolar neurons that are the receptors for smell. Sustentacular cells are supporting cells. Sustentacular cells are most numerous cell type in the olfactory epithelium.
4. What cell types are found in the respiratory mucosa?
a. Ciliated cells
b. Goblet cells
c. Basal cells
d. Brush cells
e. All of the above
Answer: e
In man, respiratory mucosa is composed of ciliated pseudostratified columnar epithelium with goblet cells. Respiratory mucosa contains several cell types: ciliated cells, goblet cells, basal cells, and brush cells. Respiratory mucosa is located lining the respiratory segment of the nasal cavity. It lines the conchae and the paranasal sinuses.
5. What type of tissue makes up the epiglottis?
a. Compact bone
b. Spongy bone
c. Hyaline cartilage
d. Fibrocartilage
e. Elastic cartilage
Answer: e
The epiglottis is part of the larynx. It is composed of elastic cartilage.
6. What is the smallest airspace of the respiratory tree?
a. Alveolar duct
b. Alveoli
c. Alveolar sac
d. Respiratory bronchiole
e. Terminal bronchiole
Answer: b
The respiratory tract is made of branching structures, much like the branches of a tree. The trachea branches into two bronchi which branch into smaller bronchi. The bronchi ultimately branch into smaller bronchioles. Bronchioles are distinguished from bronchi in that they do not have cartilage and submucosal glands. The terminal bronchioles are the last part of the airway in which gas exchange does not occur. Terminal bronchioles lead to the respiratory bronchioles. The respiratory bronchioles are the first section of the respiratory tree that gas exchange can occur. The alveoli duct is analogous to a thoroughfare with many cul-du-sacs branching off of it. At the end of the alveoli duct is an alveoli sac. An alveoli sac is a cluster of alveoli, much like a cluster of grapes. Alveoli are individual sacs where gas exchange occurs.
7. What type of epithelium lines the trachea?
a. Simple squamous epithelium
b. Simple cuboidal epithelium
c. Simple columnar epithelium
d. Stratified squamous epithelium
e. Pseudostratified epithelium
Answer: e
The trachea is lined by pseudostratified squamous epithelium. Epithelium lines body cavities and surfaces. Pseudostratified squamous epithelium is "pseudostratified" because it is only one cell layer thick, yet it appears to be stratified. In reality, every cell touches the basement membrane.
Note from Sarah Bellham: The prefix "pseudo" is of Greek origin and it means false or counterfeit. For example: pseudonym, pseudo-science or pseudostratified.
8. Which structure is part of the conducting portion of the airway?
a. Bronchi
b. Alveolar ducts
c. Alveoli
d. Alveolar sacs
e. Respiratory bronchioles
Answer: a
The conducting portion of the airway is where air is moved, warmed and moistened. The nasal cavities, pharynx, larynx, trachea and bronchi are all part of the conducting portion of the airway.
The respiratory portion of the airway is where gas exchange occurs. The respiratory bronchioles, alveolar ducts, alveolar sacs and alveoli are all part of the respiratory portion.
9. What type of epithelium lines the vestibule?
a. Simple squamous epithelium
b. Simple columnar epithelium
c. Stratified squamous epithelium
d. Ciliated pseudostratified epithelium with goblet cells
e. Transitional epithelium
Answer: c
The vestibule is lined by stratified squamous epithelium.
10. Which cartilage of the larynx is made of hyaline cartilage?
a. Thyroid cartilage
b. Cricoid cartilage
c. Arytenoid cartilage
d. Corniculate cartilage
e. All of the above
Answer: e
The larynx is composed of several cartilages. The thyroid cartilage, cricoid cartilage, arytenoid cartilages, corniculate cartilages and cuneiform cartilages are all composed of hyaline cartilage. The epiglottis is elastic cartilage. There is no fibrocartilage in the larynx.
11. What part of the respiratory tree is the functional unit where gas exchange occurs?
a. Alveolar duct
b. Alveoli
c. Alveolar sac
d. Respiratory bronchiole
e. Terminal bronchiole
Answer: b
The respiratory tract is made of branching structures, much like the branches of a tree. The trachea branches into two bronchi which branch into smaller bronchi. The bronchi ultimately branch into smaller bronchioles. Bronchioles are distinguished from bronchi in that they do not have cartilage and submucosal glands. The terminal bronchioles are the last part of the airway in which gas exchange does not occur. Terminal bronchioles lead to the respiratory bronchioles. The respiratory bronchioles are the first section of the respiratory tree that gas exchange can occur. The alveoli duct is analogous to a thoroughfare with many cul-du-sacs branching off of it. At the end of the alveoli duct is an alveoli sac. An alveoli sac is a cluster of alveoli, much like a cluster of grapes. Alveoli are individual sacs where gas exchange occurs.
12. Which cell type is involved in general sensation of the olfactory mucosa?
a. Basal cells
b. Brush cells
c. Olfactory cells
d. Sustentacular cells
e. All of the above
Answer: b
Olfactory mucosa lines the roof and portions of the walls of the nasal cavity. It contains several cell types: basal cells, brush cells, olfactory cells and sustentacular cells.
Basal cells are located in the basal lamina. Brush cells are involved with general sensation of the olfactory mucosa. Olfactory cells are bipolar neurons that are the receptors for smell. Sustentacular cells are supporting cells. Sustentacular cells are most numerous cell type in the olfactory epithelium.
13. What type of cells are found in the olfactory mucosa?
a. Basal cells
b. Brush cells
c. Olfactory cells
d. Sustentacular cells
e. All of the above
Answer: e
Olfactory mucosa lines the roof and portions of the walls of the nasal cavity. It contains several cell types: basal cells, brush cells, olfactory cells and sustentacular cells.
Basal cells are located in the basal lamina. Brush cells are involved with general sensation of the olfactory mucosa. Olfactory cells are bipolar neurons that are the receptors for smell. Sustentacular cells are supporting cells. Sustentacular cells are most numerous cell type in the olfactory epithelium.
14. What type of tissue makes up the rings of the trachea?
a. Compact bone
b. Spongy bone
c. Hyaline cartilage
d. Fibrocartilage
e. Elastic cartilage
Answer: c
The rings of the trachea are composed of hyaline cartilage.
15. Which cell is a squamous pulmonary epithelial cell?
a. Clara cell
b. Type I pneumocyte
c. Type II pneumocyte
d. Dust cell
e. Brush cell
Answer: b
The Clara cell is found in the terminal bronchioles. The type I pneumocyte is a squamous epithelial cell. It covers most of the surface of the alveoli. The type II pneumocyte is also called a septal cell. The type II pneumocyte secretes surfactant. The dust cell is also called the alveolar phagocyte. Brush cells are occasionally, but rarely, seen in the alveolar epithelium.
16. Which cell is also called an alveolar phagocyte?
a. Clara cell
b. Type I pneumocyte
c. Type II pneumocyte
d. Dust cell
e. Brush cell
Answer: d
The Clara cell is found in the terminal bronchioles. The type I pneumocyte is a squamous epithelial cell. It covers most of the surface of the alveoli. The type II pneumocyte is also called a septal cell. The type II pneumocyte secretes surfactant. The dust cell is also called the alveolar phagocyte. Brush cells are occasionally, but rarely, seen in the alveolar epithelium.
17. Which is structure is NOT part of the conducting portion of the airway?
a. Bronchi
b. Larynx
c. Trachea
d. Larynx
e. Respiratory bronchioles
Answer: e
The conducting portion of the airway is where air is moved, warmed and moistened. The nasal cavities, pharynx, larynx, trachea and bronchi are all part of the conducting portion of the airway.
The respiratory portion of the airway is where gas exchange occurs. The respiratory bronchioles, alveolar ducts, alveolar sacs and alveoli are all part of the respiratory portion.
18. What type of tissue lines the pharynx?
a. Simple squamous epithelium
b. Simple columnar epithelium
c. Stratified squamous epithelium
d. Ciliated pseudostratified epithelium with goblet cells
e. Both c and d
Answer: e
The pharynx is lined by both stratified squamous epithelium and ciliated pseudostratified epithelium with goblet cells. Different regions are lined by a different type of epithelium. Regions of the pharynx that are likely to be roughened up by food are lined by stratified squamous epithelium. Other regions of the pharynx are lined by ciliated pseudostratified epithelium with goblet cells.
19. What is an olfactory cell?
a. Unipolar neuron
b. Bipolar neuron
c. Multipolar neuron
d. Supporting cell
e. None of the above
Answer: b
An olfactory cell is a bipolar neuron.
20. Which type of cartilage is found in the larynx?
a. Hyaline cartilage
b. Elastic cartilage
c. Fibrocartilage
d. Both a and b
e. All of the above
Answer: d
The larynx is composed of several cartilages. The thyroid cartilage, cricoid cartilage, arytenoid cartilages, corniculate cartilages and cuneiform cartilages are all composed of hyaline cartilage. The epiglottis is elastic cartilage. There is no fibrocartilage in the larynx.
21. What structure is similar to a "bunch of grapes?
a. Alveolar duct
b. Alveoli
c. Alveolar sac
d. Respiratory bronchiole
e. Terminal bronchiole
Answer: c
The respiratory tract is made of branching structures, much like the branches of a tree. The trachea branches into two bronchi which branch into smaller bronchi. The bronchi ultimately branch into smaller bronchioles. Bronchioles are distinguished from bronchi in that they do not have cartilage and submucosal glands. The terminal bronchioles are the last part of the airway in which gas exchange does not occur. Terminal bronchioles lead to the respiratory bronchioles. The respiratory bronchioles are the first section of the respiratory tree that gas exchange can occur. The alveoli duct is analogous to a thoroughfare with many cul-du-sacs branching off of it. At the end of the alveoli duct is an alveoli sac. An alveoli sac is a cluster of alveoli, much like a cluster of grapes. Alveoli are individual sacs where gas exchange occurs.
22. Which cell is found in large numbers in the terminal bronchioles?
a. Clara cell
b. Type I pneumocyte
c. Type II pneumocyte
d. Dust cell
e. Brush cell
Answer: a
The Clara cell is found in the terminal bronchioles. The type I pneumocyte is a squamous epithelial cell. It covers most of the surface of the alveoli. The type II pneumocyte is also called a septal cell. The type II pneumocyte secretes surfactant. The dust cell is also called the alveolar phagocyte. Brush cells are occasionally, but rarely, seen in the alveolar epithelium.
23. Which cell type is located at the basal lamina of the olfactory mucosa?
a. Basal cells
b. Brush cells
c. Olfactory cells
d. Sustentacular cells
e. All of the above
Answer: a
Olfactory mucosa lines the roof and portions of the walls of the nasal cavity. It contains several cell types: basal cells, brush cells, olfactory cells and sustentacular cells.
Basal cells are located in the basal lamina. Brush cells are involved with general sensation of the olfactory mucosa. Olfactory cells are bipolar neurons that are the receptors for smell. Sustentacular cells are supporting cells. Sustentacular cells are most numerous cell type in the olfactory epithelium.
24. Which cell type is most numerous in olfactory mucosa?
a. Basal cells
b. Brush cells
c. Olfactory cells
d. Sustentacular cells
e. None of the above
Answer: d
Olfactory mucosa lines the roof and portions of the walls of the nasal cavity. It contains several cell types: basal cells, brush cells, olfactory cells and sustentacular cells.
Basal cells are located in the basal lamina. Brush cells are involved with general sensation of the olfactory mucosa. Olfactory cells are bipolar neurons that are the receptors for smell. Sustentacular cells are supporting cells. Sustentacular cells are most numerous cell type in the olfactory epithelium.
25. What type of epithelium is found in the respiratory mucosa of man?
a. Non-ciliated pseudostratified columnar epithelium with goblet cells
b. Ciliated pseudostratified columnar epithelium with goblet cells
c. Simple columnar epithelium
d. Stratified squamous epithelium
e. Transitional epithelium
Answer: b
In man, respiratory mucosa is composed of ciliated pseudostratified columnar epithelium with goblet cells. Respiratory mucosa contains several cell types: ciliated cells, goblet cells, basal cells, and brush cells. Respiratory mucosa is located lining the respiratory segment of the nasal cavity. It lines the conchae and the paranasal sinuses.
26. What type of tissue makes up the "Adam's apple"?
a. Compact bone
b. Spongy bone
c. Hyaline cartilage
d. Fibrocartilage
e. Elastic cartilage
Answer: e
The "Adam's apple" is a nickname for part of the larynx formed by the thyroid cartilage. The thyroid cartilage is composed of hyaline cartilage.
27. What type of tissue forms the alveoli in the lung?
a. Simple squamous epithelium
b. Simple cuboidal epithelium
c. Simple columnar epithelium
d. Stratified squamous epithelium
e. Pseudostratified epithelium
Answer: a
The alveoli are formed by simple squamous epithelium. Epithelium lines body cavities and surfaces. Simple squamous epithelium is "simple" because it is one cell thick. "Squamous" refers to the fact that the cells are flat.
28. What type of tissue lines the paranasal sinuses?
a. Simple squamous epithelium
b. Simple columnar epithelium
c. Stratified squamous epithelium
d. Ciliated pseudostratified epithelium with goblet cells
e. Transitional epithelium
Answer: d
The paranasal sinuses are lined by ciliated pseudostratified epithelium with goblet cells.
29. In which structure does gas exchange NOT occur?
a. Alveolar duct
b. Alveoli
c. Alveolar sac
d. Respiratory bronchiole
e. Terminal bronchiole
Answer: e
The respiratory tract is made of branching structures, much like the branches of a tree. The trachea branches into two bronchi which branch into smaller bronchi. The bronchi ultimately branch into smaller bronchioles. Bronchioles are distinguished from bronchi in that they do not have cartilage and submucosal glands. The terminal bronchioles are the last part of the airway in which gas exchange does not occur. Terminal bronchioles lead to the respiratory bronchioles. The respiratory bronchioles are the first section of the respiratory tree that gas exchange can occur. The alveoli duct is analogous to a thoroughfare with many cul-du-sacs branching off of it. At the end of the alveoli duct is an alveoli sac. An alveoli sac is a cluster of alveoli, much like a cluster of grapes. Alveoli are individual sacs where gas exchange occurs.
30. Which cell secretes surfactant?
a. Clara cell
b. Type I pneumocyte
c. Type II pneumocyte
d. Dust cell
e. Brush cell
Answer: c
The Clara cell is found in the terminal bronchioles. The type I pneumocyte is a squamous epithelial cell. It covers most of the surface of the alveoli. The type II pneumocyte is also called a septal cell. The type II pneumocyte secretes surfactant. The dust cell is also called the alveolar phagocyte. Brush cells are occasionally, but rarely, seen in the alveolar epithelium.
31. Which cartilage of the larynx is made of elastic cartilage?
a. Thyroid cartilage
b. Cricoid cartilage
c. Arytenoid cartilage
d. Epiglottis
e. Corniculate cartilage
Answer: d
The larynx is composed of several cartilages. The thyroid cartilage, cricoid cartilage, arytenoid cartilages, corniculate cartilages and cuneiform cartilages are all composed of hyaline cartilage. The epiglottis is elastic cartilage. There is no fibrocartilage in the larynx.
32. Which cell is rarely found in the alveolus?
a. Clara cell
b. Type I pneumocyte
c. Type II pneumocyte
d. Dust cell
e. Brush cell
Answer: e
The Clara cell is found in the terminal bronchioles. The type I pneumocyte is a squamous epithelial cell. It covers most of the surface of the alveoli. The type II pneumocyte is also called a septal cell. The type II pneumocyte secretes surfactant. The dust cell is also called the alveolar phagocyte. Brush cells are occasionally, but rarely, seen in the alveolar epithelium.
33. What are the alveolar pores called?
a. Pores of Luschka
b. Pores of Descemet
c. Pores of Mall
d. Pores of Kohn
e. Pores of Disse
Answer: d
The alveolar pores are the pores of Kohn. These are openings between adjacent alveoli.
34. What is the first portion of the respiratory tree where gas exchange can occur?
a. Alveolar duct
b. Alveoli
c. Alveolar sac
d. Respiratory bronchiole
e. Terminal bronchiole
Answer: d
The respiratory tract is made of branching structures, much like the branches of a tree. The trachea branches into two bronchi which branch into smaller bronchi. The bronchi ultimately branch into smaller bronchioles. Bronchioles are distinguished from bronchi in that they do not have cartilage and submucosal glands. The terminal bronchioles are the last part of the airway in which gas exchange does not occur. Terminal bronchioles lead to the respiratory bronchioles. The respiratory bronchioles are the first section of the respiratory tree that gas exchange can occur. The alveoli duct is analogous to a thoroughfare with many cul-du-sacs branching off of it. At the end of the alveoli duct is an alveoli sac. An alveoli sac is a cluster of alveoli, much like a cluster of grapes. Alveoli are individual sacs where gas exchange occurs.
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